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MYP_034408
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Basic Information
Protonectin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
12 amino acids
C58H107N13O14
Standard
Sequence
ILGTILGLLKGL
Physicochemical Analysis
1210.55 Da
8.75
0.76
0.55
0.0633
1.85
0.38
0.66
20.04
227.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
429.67
-0.54
15.0
15.0
42.0
85.0
0.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0231520 VERIFIED: YES
Provenance & Taxonomy
Agelaia pallipes [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae ATCC 700603
128 μM
MIC
PMID28299840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28299840/
RECORD: Rec_0232339 VERIFIED: YES
Provenance & Taxonomy
Agelaia pallipes pallipes [Animal]
MCD; Protonectin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Hemolytic
S. epidermis
PMID15052574;15225564;23836163 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15052574/
RECORD: Rec_0234774 VERIFIED: YES
Provenance & Taxonomy
Protonectarina sylveirae [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli
20-64 μM
MIC
PaperStructural and biological characterization of two novel peptides from the venom of the neotropical social wasp Agelaia pallipes pallipes
RECORD: Rec_0237517 VERIFIED: YES
Provenance & Taxonomy
Agelaia pallipes pallipes [Animal]
Protonectin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Chemotactic Immunomodulatory
PaperToxicon. 2004 Jul;44(1):67-74 | http://www.ncbi.nlm.nih.gov/pubmed/15225564 PMID15225564 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15225564/
RECORD: Rec_0239056 VERIFIED: YES
Provenance & Taxonomy
Agelaia pallipes [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
C. albicans14-4
16 μM
MIC
PMID28299840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28299840/
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