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MYP_034392
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Basic Information
Leucocin A
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
37 amino acids
C174H248N52O50S2
Standard
Sequence
KYYGNGVHCTKSGCSVNWGEAFSAGVHRLANGGNGFW
Physicochemical Analysis
3932.28 Da
8.82
1.91
1.57
0.0517
-0.39
0.53
0.12
-1.50
42.16
0.1622
13980.00
14105.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1644.84
-20.16
60.0
56.0
123.0
278.0
10.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0302056 VERIFIED: YES
Provenance & Taxonomy
Leuconostoc pseudomesenteroides QU 15 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Bacillus circulans JCM 2504T
0.15
MIC
PMID20070442 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20070442/
RECORD: Rec_0304756 VERIFIED: YES
Provenance & Taxonomy
Leuconostoc mesenteroides [Bacterium]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0305527 VERIFIED: YES
Provenance & Taxonomy
Leuconostoc gelidum [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial
S. pneumoniae CIP 102911
0.256 μM
MIC
PaperCharacterization of leucocin A-UAL 187 and cloning of the bacteriocin gene from Leuconostoc gelidum
RECORD: Rec_0333574 VERIFIED: NO
Provenance & Taxonomy
Leuconostoc gelidum [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0333615 VERIFIED: YES
Provenance & Taxonomy
Leuconostoc gelidum [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial
L. sakei subsp. sakei CIP 103139
0.008 μM
MIC
PaperCharacterization of leucocin A-UAL 187 and cloning of the bacteriocin gene from Leuconostoc gelidum
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