Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC449H708N126O131S8

DescriptionStandard

        MRTLAILAAILLVALQAQAEPLQARGDEFAAAQEQIPADNPEVVVSLAWDESLAPKDSGSRKNMACACRIPSCFAGERRYGTCFYLGRVWAFCC
    

Molecular Weight10223.71 Da

Isoelectric Point (pI)5.28

Net Charge (pH 7.0)-1.54

Net Charge (pH 7.4) -1.86

Charge Density (pH 7.0) -0.0164

GRAVY Index0.16

Hydrophobic Moment 0.48

Boman Index0.09

Instability Index56.37

Aliphatic Index 87.45

Aromaticity 0.0851

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4099.29

LogP -39.22

H-bond Donors 147.0

H-bond Acceptors 138.0

Rotatable Bonds 329.0

Heavy Atoms 714.0

Ring Count 15.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0137918 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Animal]

FamilyDefensin

Tax ID9601

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence