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MYP_034305
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Basic Information
Schmackerin-C1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
17 amino acids
C84H129N23O20S2
Standard
Sequence
AAPRGGKGFFCKLFKDC
Physicochemical Analysis
1845.19 Da
9.39
2.77
2.55
0.1632
-0.10
0.55
0.00
-5.25
34.71
0.1765
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
697.39
-5.65
26.0
25.0
60.0
129.0
4.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0025461 VERIFIED: YES
Provenance & Taxonomy
Odorrana schmackeri [Animal]
Schmackerin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
11-17
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
54.2 μM
MIC
PaperX. Yang et al. / Journal of Proteome Research 11 (2012) 306-319. Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
RECORD: Rec_0032072 VERIFIED: YES
Provenance & Taxonomy
Odorrana schmackeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
11-17
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
100 μg/mL
MIC
PaperExtremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
RECORD: Rec_0108336 VERIFIED: YES
Provenance & Taxonomy
Odorrana schmackeri [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
11-17
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Bacillus pyocyaneus CMCCB 10104
50 μg/mL
MIC
PaperExtremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs. J Proteome Res. 2012 Jan 1;11(1):306-19. doi: 10.1021/pr200782u. PMID: 22029824. PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
RECORD: Rec_0141451 VERIFIED: YES
Provenance & Taxonomy
Odorrana schmackeri [Animal]
Schmackerin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
11-17
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
27.1 μM
MIC
PaperX. Yang et al. / Journal of Proteome Research 11 (2012) 306-319. Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
RECORD: Rec_0245493 VERIFIED: YES
Provenance & Taxonomy
Odorrana schmackeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
11-17
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus
50 μg/mL
MIC
PaperExtremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
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