Peptide Database

Peptide NamePelophylaxin-HB2 antimicrobial peptide

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC341H572N90O107S4

DescriptionStandard

        MFTTKKSLLLVFFLGTIALSLCQEERGADDENGGEITDEEIKRGILADTLKGAAKNVAGVLLDKLKCKITGGC
    

Molecular Weight7772.99 Da

Isoelectric Point (pI)5.30

Net Charge (pH 7.0)-1.51

Net Charge (pH 7.4) -1.80

Charge Density (pH 7.0) -0.0208

GRAVY Index0.09

Hydrophobic Moment 0.53

Boman Index0.08

Instability Index12.40

Aliphatic Index 105.62

Aromaticity 0.0411

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3191.89

LogP -30.51

H-bond Donors 113.0

H-bond Acceptors 110.0

Rotatable Bonds 275.0

Heavy Atoms 542.0

Ring Count 3.0

Amide Bonds 75.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0190414 VERIFIED: NO

Provenance & Taxonomy

OrganismPelophylax hubeiensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence