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MYP_034264
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Basic Information
Peptide-VIII
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
12 amino acids
C72H128N18O13S
Standard
Sequence
GKWMKLLKKILK
Physicochemical Analysis
1485.96 Da
10.60
4.76
4.54
0.3963
-0.25
0.84
-0.08
9.57
130.00
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
529.31
0.67
19.0
19.0
56.0
104.0
2.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0319161 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
methicillin-resistant Staphylococcus aureus (Clinical isolate from Motol University Hospital)
5.7
MIC
PMID31107198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31107198/
RECORD: Rec_0329111 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans N873
25 μM
MIC
PMID30753486 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30753486/
RECORD: Rec_0334543 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus Epidermidis (Clinical isolate from Motol University Hospital)
2.3
MIC
PMID31107198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31107198/
RECORD: Rec_0375717 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
C. tropicalis ATCC 750
PMID28600071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28600071/
RECORD: Rec_0410728 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
methicillin-resistant Staphylococcus aureus (Clinical isolate from Liberec Regional Hospital)
3.6
MIC
PMID31107198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31107198/
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