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MYP_034244
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Basic Information
Magainin-2 [S8K,A9V,K10G,K11S,G13I,A15S,F16W,V17K]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
23 amino acids
C119H187N31O30S
Standard
Sequence
GIGKFLHKVGSFIKSWKGEIMNS
Physicochemical Analysis
2564.01 Da
10.00
2.85
2.59
0.1237
-0.07
0.68
0.16
2.81
80.43
0.1304
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
993.15
-7.41
35.0
35.0
89.0
181.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0062128 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
36-73 μM
MIC
PMID9335545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9335545/
RECORD: Rec_0106447 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
24 μM
Paperhttps://pubmed.ncbi.nlm.nih.gov/9335545/ PMID9335545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9335545/
RECORD: Rec_0131875 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
5 μM
MIC
PMID9335545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9335545/
RECORD: Rec_0186219 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
73 μM
MIC
PMID9335545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9335545/
RECORD: Rec_0240131 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
24 μM
Hemolysis
PMID9335545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9335545/
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