Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC816H1214N208O239S10

DescriptionStandard

        MAWLLQAHFISCSFVLCTLYFRLFTGWFVERCWKNDVGYCRKRCLHLERYKLLCMNKLSCCIPLSSDNPYTQWPIHPTFSEDVTFGFGTHDGFPFSPVSGLDDEVTIKTTKTQETTVTGTTASERNSTWTLTTVPQSVEGTTFSHEPETADLYKHWD
    

Molecular Weight18082.27 Da

Isoelectric Point (pI)5.83

Net Charge (pH 7.0)-4.03

Net Charge (pH 7.4) -4.71

Charge Density (pH 7.0) -0.0257

GRAVY Index-0.27

Hydrophobic Moment 0.47

Boman Index0.05

Instability Index39.72

Aliphatic Index 63.89

Aromaticity 0.1401

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 40950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7120.75

LogP -67.65

H-bond Donors 259.0

H-bond Acceptors 251.0

Rotatable Bonds 569.0

Heavy Atoms 1273.0

Ring Count 42.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0202738 VERIFIED: NO

Provenance & Taxonomy

OrganismPhocoena sinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence