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MYP_034166
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Basic Information
Diketopiperazine (preWY)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
2 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XY
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0121993 VERIFIED: YES
Provenance & Taxonomy
Neobellieria bullata [other]
Structure & Mods
cyclic peptide topology [Cyclic]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial
Human ovarian adenocarcinoma A2780
89.8 μM
IC50
PMID12570666;18044819;24168419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12570666/
RECORD: Rec_0126848 VERIFIED: YES
Provenance & Taxonomy
Neobellieria bullata [other]
Structure & Mods
cyclic peptide topology [Cyclic]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 12600
16 μg/mL
MIC
PMID12570666;18044819;24168419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12570666/
RECORD: Rec_0129814 VERIFIED: YES
Provenance & Taxonomy
Neobellieria bullata [other]
Structure & Mods
cyclic peptide topology [Cyclic]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial
Micrococcus luteus DPMB3
24000 μM
MIC
PMID12570666;18044819;24168419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12570666/
RECORD: Rec_0143211 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Prenylated-Trp
Bio-Activity Profile
Antimicrobial Anticancer
A2780
89.8 μM
IC50
PMID22617493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22617493/
RECORD: Rec_0145031 VERIFIED: YES
Provenance & Taxonomy
Neobellieria bullata [other]
Structure & Mods
cyclic peptide topology [Cyclic]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 1
Bio-Activity Profile
Hemolytic
Human erythrocytes (- at NA
Hemolysis
PMID12570666;18044819;24168419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12570666/
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