‹ ›
MYP_034155
← PREVIOUS NEXT → BACK
Basic Information
KLW-L10-Nala
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
18 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KWKKLLKKLXKLLKKLLK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0010369 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=NAla
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
NIH 3T3
2 μM
IC50
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0042320 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 10
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli KCTC 1682
4 μM
MIC
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0054445 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
residue-level stereochemical modification [Mixed]
None
Amidation
a=Nala (Ala-peptoid)
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0072530 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=NAla
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: SK-OV-3
0.9 μM
IC50
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0081106 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 10
Bio-Activity Profile
Antimicrobial Antibacterial
Human skin melanoma SK-MEL-2
1.3 μM
IC50
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 1 of 4