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MYP_034152
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Basic Information
Insulin-like growth factor I-A
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
70 amino acids
C336H514N100O103S7
Standard
Sequence
GPETLCGAELVDTLQFVCGDRGFYFSKPTGYGSNNRRSHHRGIVDECCFQSCDFRRLEMYCAPAKQAKSA
Physicochemical Analysis
7826.74 Da
7.78
0.88
0.47
0.0126
-0.51
0.48
-0.11
56.07
47.43
0.1143
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3288.05
-38.62
121.0
113.0
255.0
546.0
13.0
74.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0129170 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Insulin-like growth factor I
8355
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-48; 18-61; 47-52
Bio-Activity Profile
Hormone Endocrine Growth regulation Development regulation Receptor modulation
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Insulin-like growth factor I-A (Xenopus laevis): PMID 11944947 PMID11944947 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11944947/
RECORD: Rec_0135208 VERIFIED: NO
Provenance & Taxonomy
Xenopus laevis [Animal]
Insulin
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Metabolic
Evidence URLhttps://www.uniprot.org/uniprotkb/IGF1A_XENLA/entry
RECORD: Rec_0145491 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0221502 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Insulin-like growth factor I
8355
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-48; 18-61; 47-52
Bio-Activity Profile
Hormone Endocrine Growth regulation Development regulation Receptor modulation
integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Insulin-like growth factor I-A (Xenopus laevis): PMID 11944947 PMID11944947 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11944947/