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MYP_034139
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Basic Information
Rhesus theta defensin-1 2 subunit B (RTD-1 subunit B) (RTD-1b) (Demidefensin-1) (RTD-2)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Anti-HIV
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
76 amino acids
C347H576N112O105S6
Standard
Sequence
MRTFALLTAMLLLVALHAQAEARQARADEAAAQQQPGADDQGMAHSFTRPENAALPLSESARGLRCLCRRGVCQLL
Physicochemical Analysis
8189.36 Da
7.79
0.66
0.29
0.0087
-0.06
0.82
-0.02
39.59
90.26
0.0263
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3499.21
-39.71
124.0
114.0
273.0
570.0
7.0
83.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0108120 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Alpha-defensin; Defensin
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Listeria monocytogenes (Gram-positive)
PMID10521339;11527997;11675394;23148585 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10521339/
RECORD: Rec_0171011 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
Evidence URLhttps://patents.google.com/patent/US20030144184A1/en PatentUS 2003/0144184 A1
RECORD: Rec_0172920 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Alpha-defensin; Defensin
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
C. neoformans
PMID10521339;11527997;11675394;23148585 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10521339/
RECORD: Rec_0217565 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Alpha-defensin; Defensin
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Candida albicans
PMID10521339;11527997;11675394;23148585 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10521339/
RECORD: Rec_0339542 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Alpha-defensin; Defensin
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Escherichia coli (Gram-negative)
PMID10521339;11527997;11675394;23148585 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10521339/
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