Peptide Database

Peptide NamePlatelet-derived growth factor subunit A

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length125 amino acids

Chemical FormulaC617H1027N191O183S8

DescriptionStandard

        SIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTGRPRESGKKRKRKRLKPT
    

Molecular Weight14305.45 Da

Isoelectric Point (pI)9.57

Net Charge (pH 7.0)11.66

Net Charge (pH 7.4) 11.14

Charge Density (pH 7.0) 0.0933

GRAVY Index-0.79

Hydrophobic Moment 0.66

Boman Index-0.28

Instability Index47.39

Aliphatic Index 68.48

Aromaticity 0.0400

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6097.50

LogP -66.81

H-bond Donors 223.0

H-bond Acceptors 206.0

Rotatable Bonds 480.0

Heavy Atoms 999.0

Ring Count 19.0

Amide Bonds 130.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0110645 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyPDGF/VEGF growth factor family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide10-54; 43-91; 47-93

Bio-Activity Profile

Function

Cytokine Growth factor PDGF VEGF growth factor family Growth factor signaling Angiogenic