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MYP_034126
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Basic Information
mBD-7
Antimicrobial
Standard
37 amino acids
C187H295N59O49S6
Standard
Sequence
NSKRACYREGGECLQRCIGLFHKIGTCNFRFKCCKFQ
Physicochemical Analysis
4346.10 Da
9.34
5.79
5.44
0.1564
-0.48
0.73
-0.20
46.72
44.86
0.1351
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1798.93
-19.00
70.0
62.0
149.0
301.0
6.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004924 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
PaperStructure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity.
RECORD: Rec_0009156 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20060034820A1/en PatentUS 2006/0034820 A1
RECORD: Rec_0083198 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID11714914 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11714914/
RECORD: Rec_0095821 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0273454 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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