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MYP_034124
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Basic Information
Enterocin AS-48 (AS-48; Bacteriocin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
70 amino acids
C328H549N87O89S
Standard
Sequence
MAKEFGIPAAVAGTVINVVEAGGWVTTIVSILTAVGSGGLSLLAAAGRESIKAYLKKEIKKKGKRAVIAW
Physicochemical Analysis
7167.46 Da
10.09
5.50
5.27
0.0786
0.55
0.72
0.25
18.82
117.14
0.0571
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2800.33
-23.14
100.0
96.0
243.0
505.0
7.0
70.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0170032 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecalis [Bacterium]
Enterocin
1351
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Hydrogen bonds between Ala-2 and Ile-7, Val-18 and Gly-23, Thr-33 and Gly-36, the backbone carbonyl oxygen of Phe-5 and the side-chain hydroxylic proton of Ser-50
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
PaperPubMed PMID: 2501837 | PubMed PMID: 14623193 | PubMed PMID: 11005847 PMID2501837;14623193;11005847 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2501837/
RECORD: Rec_0198287 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecalis [Bacterium]
Enterocin
1351
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Hydrogen bonds between Ala-2 and Ile-7, Val-18 and Gly-23, Thr-33 and Gly-36, the backbone carbonyl oxygen of Phe-5 and the side-chain hydroxylic proton of Ser-50
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus faecalis
PaperPubMed PMID: 2501837 | PubMed PMID: 14623193 | PubMed PMID: 11005847 PMID2501837;14623193;11005847 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2501837/
RECORD: Rec_0218808 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecalis [Bacterium]
Enterocin
1351
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Hydrogen bonds between Ala-2 and Ile-7, Val-18 and Gly-23, Thr-33 and Gly-36, the backbone carbonyl oxygen of Phe-5 and the side-chain hydroxylic proton of Ser-50
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PaperPubMed PMID: 2501837 | PubMed PMID: 14623193 | PubMed PMID: 11005847 PMID2501837;14623193;11005847 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2501837/
RECORD: Rec_0251382 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecalis [Bacterium]
Enterocin
1351
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Hydrogen bonds between Ala-2 and Ile-7, Val-18 and Gly-23, Thr-33 and Gly-36, the backbone carbonyl oxygen of Phe-5 and the side-chain hydroxylic proton of Ser-50
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus circulans
PaperPubMed PMID: 2501837 | PubMed PMID: 14623193 | PubMed PMID: 11005847 PMID2501837;14623193;11005847 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2501837/
RECORD: Rec_0260286 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecalis [Bacterium]
Enterocin
1351
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Hydrogen bonds between Ala-2 and Ile-7, Val-18 and Gly-23, Thr-33 and Gly-36, the backbone carbonyl oxygen of Phe-5 and the side-chain hydroxylic proton of Ser-50
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Nocardia corrallina
PaperPubMed PMID: 2501837 | PubMed PMID: 14623193 | PubMed PMID: 11005847 PMID2501837;14623193;11005847 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2501837/
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