Peptide Database

Peptide NameRelaxin-3 A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC102H168N28O36S4

DescriptionStandard

        DVLAGLSSNCCKWGCSKSEISSLC
    

Molecular Weight2490.85 Da

Isoelectric Point (pI)6.04

Net Charge (pH 7.0)-0.28

Net Charge (pH 7.4) -0.54

Charge Density (pH 7.0) -0.0116

GRAVY Index0.30

Hydrophobic Moment 0.31

Boman Index0.11

Instability Index36.16

Aliphatic Index 81.25

Aromaticity 0.0417

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1039.52

LogP -14.46

H-bond Donors 41.0

H-bond Acceptors 40.0

Rotatable Bonds 83.0

Heavy Atoms 170.0

Ring Count 2.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0030342 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyRelaxin

Tax ID9823

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide10-15

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Receptor modulation

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0177130 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0382777 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyInsulin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic