Peptide Database

Peptide NameGnRH

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Reproductive neuropeptide

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC53H74N16O13S

DescriptionStandard

        CHWSYGLRPG
    

Molecular Weight1175.32 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)0.84

Net Charge (pH 7.4) 0.57

Charge Density (pH 7.0) 0.0836

GRAVY Index-0.68

Hydrophobic Moment 0.40

Boman Index0.04

Instability Index68.75

Aliphatic Index 39.00

Aromaticity 0.2000

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 463.26

LogP -3.60

H-bond Donors 18.0

H-bond Acceptors 16.0

Rotatable Bonds 32.0

Heavy Atoms 83.0

Ring Count 5.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0035513 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGnRH

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Reproductive neuropeptide

RECORD: Rec_0212975 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0370023 VERIFIED: YES

Provenance & Taxonomy

OrganismUnknown [Animal]

FamilyGnRH

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine ACE inhibitory

Half-LifeMammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour