Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC442H731N129O126S8

DescriptionStandard

        MKLLVLFLAILLAIEEPVVSVECWMDGHCRLLCRDDEDSIIRCRNRKRCCVPSRYLTIEPVTIHGILDWTTPQISTTAPQTKRNKSRG
    

Molecular Weight10124.84 Da

Isoelectric Point (pI)8.64

Net Charge (pH 7.0)2.63

Net Charge (pH 7.4) 2.21

Charge Density (pH 7.0) 0.0299

GRAVY Index-0.07

Hydrophobic Moment 0.59

Boman Index-0.05

Instability Index72.63

Aliphatic Index 102.95

Aromaticity 0.0455

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4109.54

LogP -37.03

H-bond Donors 152.0

H-bond Acceptors 139.0

Rotatable Bonds 335.0

Heavy Atoms 705.0

Ring Count 13.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418912 VERIFIED: NO

Provenance & Taxonomy

OrganismAotus nancymaae [Animal]

FamilyDefensin

Tax ID37293

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence