Peptide Database

Peptide NameExtended FMRFamide-10

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC50H76N14O18

DescriptionStandard

        PASDSGFLRDP
    

Molecular Weight1161.22 Da

Isoelectric Point (pI)4.21

Net Charge (pH 7.0)-1.04

Net Charge (pH 7.4) -1.10

Charge Density (pH 7.0) -0.0945

GRAVY Index-0.75

Hydrophobic Moment 0.21

Boman Index-0.10

Instability Index61.62

Aliphatic Index 44.55

Aromaticity 0.0909

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 508.50

LogP -6.69

H-bond Donors 18.0

H-bond Acceptors 17.0

Rotatable Bonds 34.0

Heavy Atoms 82.0

Ring Count 3.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0254861 VERIFIED: YES

Provenance & Taxonomy

OrganismTyrannophasma gladiator [Animal]

FamilyExtended FMRFamide

Tax ID270861

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: >20 hour; Yeast: >20 hour; E. coli: ?

RECORD: Rec_0282113 VERIFIED: YES

Provenance & Taxonomy

OrganismTyrannophasma gladiator [Animal]

FamilyFMRFamide related peptide

Tax ID270861

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0301932 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/