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MYP_034078
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Basic Information
Toxin Cm38
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
19 amino acids
C95H145N25O28S2
Standard
Sequence
ARDGYIVDEKGCKFACFIN
Physicochemical Analysis
2149.45 Da
6.15
-0.22
-0.45
-0.0117
-0.05
0.39
0.02
11.28
66.84
0.1579
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
876.28
-7.32
32.0
30.0
71.0
150.0
3.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006429 VERIFIED: YES
Provenance & Taxonomy
Centruroides margaritatus [Animal]
Long (4 C-C) scorpion toxin; Sodium channel inhibitor
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Toxin Hemolytic
Staphylococcus aureus
PMID25633390 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25633390/
RECORD: Rec_0060946 VERIFIED: YES
Provenance & Taxonomy
Centruroides margaritatus [Animal]
Long (4 C-C) scorpion toxin; Sodium channel inhibitor
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Toxin Hemolytic
Klebsiella pneumoniae
PMID25633390 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25633390/
RECORD: Rec_0078890 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 47.4%, C 52.6% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0254850 VERIFIED: YES
Provenance & Taxonomy
Arthropoda [Animal]
6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID25671663 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25671663/
RECORD: Rec_0330923 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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