Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length483 amino acids

Chemical FormulaC2381H3808N622O685S14

DescriptionStandard

        MARGPDNMPSWTALVVLAALGTAGTATTNPGIVARITQKGLDYASQQGVAALQKVLEKMEIPSFSGSFKIKHLGKGSYNLYSIVVRGVQLPNSQIKLLPNEGLELSVTNANIKISGKWKARKDFIKSSGNFDLKVEGISISAGLKLSCDPTSGHSNITCSSCSSHIDRVRVHVSRSSMGWLIQLFYKKIENSLRDTMNRKICKAVTDSVSSKLEPYFQTLPVTAKIDNVAGIDYSLLAPPTVTAETLDGQLKGEFFSLAHRSPPPFAPPALAVPSDHDRMIYLVISDYFFNTAGLVYQQAGVLNLTVKDDMIPKESKFRLTTESFGILIPQVAKMFPNMTVQLLIWVSSLPHLTVSPAGLALTPALEAQAFAVLPNSSLAPLFLLGLTTNLSVEVGIKSDRLVGELSVDKLFLKLKHSDIGNFSVESLQSIMNYVVPSAVLPKVNERLQKGFPLPLPTHIQLLNLLLQSHQDFLLFGADVHYS
    

Molecular Weight52556.37 Da

Isoelectric Point (pI)9.11

Net Charge (pH 7.0)8.45

Net Charge (pH 7.4) 7.51

Charge Density (pH 7.0) 0.0175

GRAVY Index0.11

Hydrophobic Moment 0.73

Boman Index0.14

Instability Index35.76

Aliphatic Index 104.14

Aromaticity 0.0745

Extinction Coeff. Reduced 38390.00

Extinction Coeff. Oxidized 38640.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0314356 VERIFIED: NO

Provenance & Taxonomy

OrganismRhinolophus ferrumequinum [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria