Peptide Database

Peptide NameSyn-safencin-64

Function Ontology

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC141H243N43O31

DescriptionStandard

        AGKEKIRKKLKNEIKKKGRKWVIAW
    

Molecular Weight3036.71 Da

Isoelectric Point (pI)10.84

Net Charge (pH 7.0)8.79

Net Charge (pH 7.4) 8.59

Charge Density (pH 7.0) 0.3517

GRAVY Index-1.28

Hydrophobic Moment 0.67

Boman Index-0.43

Instability Index-6.47

Aliphatic Index 82.00

Aromaticity 0.0800

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1268.97

LogP -7.08

H-bond Donors 46.0

H-bond Acceptors 40.0

Rotatable Bonds 114.0

Heavy Atoms 215.0

Ring Count 4.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0197160 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic Toxicity

TargetTHP-1 cells

Activity<20 μM

MethodCC50

RECORD: Rec_0356783 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic

TargetL. donovani

Activity0.33 μM

MethodIC50