Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length149 amino acids

Chemical FormulaC626H1043N183O207S13

DescriptionStandard

        MKSLLSTLVIIMFLAHLVTGGWYVKKCANTLGNCRKMCRDGEKQTEPATSKCPIGKLCCVLDFKISGHCGGGGQNSDNLVTAGGDEGSNAKASTAAMVGAAAMAGTPTKTSTTAKASAAAMAGNTTKASTAAIASTPTQASAPTKANST
    

Molecular Weight14861.93 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)7.60

Net Charge (pH 7.4) 7.16

Charge Density (pH 7.0) 0.0510

GRAVY Index-0.03

Hydrophobic Moment 0.71

Boman Index0.09

Instability Index15.40

Aliphatic Index 65.10

Aromaticity 0.0268

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6220.97

LogP -89.27

H-bond Donors 224.0

H-bond Acceptors 230.0

Rotatable Bonds 495.0

Heavy Atoms 1029.0

Ring Count 12.0

Amide Bonds 158.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0147143 VERIFIED: NO

Provenance & Taxonomy

OrganismMus spicilegus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence