Peptide Database

Peptide NameCardioacceleratory Peptide 2b

Function Ontology

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myoactive peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Visceral muscle modulation

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC48H71N11O12

DescriptionStandard

        ELYAFPRV
    

Molecular Weight994.14 Da

Isoelectric Point (pI)6.10

Net Charge (pH 7.0)-0.16

Net Charge (pH 7.4) -0.34

Charge Density (pH 7.0) -0.0205

GRAVY Index0.21

Hydrophobic Moment 0.48

Boman Index0.13

Instability Index53.00

Aliphatic Index 97.50

Aromaticity 0.2500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 377.66

LogP -0.66

H-bond Donors 13.0

H-bond Acceptors 12.0

Rotatable Bonds 28.0

Heavy Atoms 71.0

Ring Count 3.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0257006 VERIFIED: YES

Provenance & Taxonomy

OrganismManduca sexta [Animal]

FamilyPeriviscerokinin

Tax ID7130

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Visceral activity Myoactive

RECORD: Rec_0311669 VERIFIED: YES

Provenance & Taxonomy

OrganismManduca sexta [Animal]

FamilyCardioacceleratory Peptide 2b

Tax ID7130

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Myotropic

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0319329 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyCAPA

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/