Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length120 amino acids

Chemical FormulaC546H902N146O167S15

DescriptionStandard

        MKSLLFTLAVFMLLAQLVSGNLYVKRCLNDVGICKKTCKPEEVRSEHGWVMCGKHKACCVPADKRSAYPSFCVLTATATATATTATATATTATTATTLMMSNGLMSSMTTMAATPVSPTT
    

Molecular Weight12664.86 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)5.61

Net Charge (pH 7.4) 5.17

Charge Density (pH 7.0) 0.0467

GRAVY Index0.30

Hydrophobic Moment 0.53

Boman Index0.15

Instability Index47.48

Aliphatic Index 74.08

Aromaticity 0.0500

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4955.50

LogP -58.45

H-bond Donors 184.0

H-bond Acceptors 190.0

Rotatable Bonds 410.0

Heavy Atoms 874.0

Ring Count 14.0

Amide Bonds 123.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0182982 VERIFIED: NO

Provenance & Taxonomy

OrganismCercocebus atys [Animal]

FamilyDefensin

Tax ID9531

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence