Peptide Database

Peptide NamePromotilin

Function Ontology

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC457H757N133O142S

DescriptionStandard

        FVPIFTHSELQRIREKERNKGQKKSLIVQQRSEEVGPLDPVEPPEEEENEVIKLTAPVAIGTRMNSRQLEKYRAALEGLLSEVLLPARNDK
    

Molecular Weight10418.77 Da

Isoelectric Point (pI)5.92

Net Charge (pH 7.0)-1.12

Net Charge (pH 7.4) -1.41

Charge Density (pH 7.0) -0.0123

GRAVY Index-0.75

Hydrophobic Moment 0.55

Boman Index-0.19

Instability Index61.10

Aliphatic Index 92.09

Aromaticity 0.0330

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4493.49

LogP -43.37

H-bond Donors 151.0

H-bond Acceptors 143.0

Rotatable Bonds 359.0

Heavy Atoms 733.0

Ring Count 11.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066954 VERIFIED: NO

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyMotilin

Tax ID9685

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Gastrointestinal

RECORD: Rec_0152463 VERIFIED: YES

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyPromotilin

Tax ID9685

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Myotropic Receptor modulation

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0370053 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/