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MYP_033923
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Basic Information
Obestatin-23
Cardiovascular
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Sleep regulation
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
23 amino acids
C114H173N33O32
Standard
Sequence
FNAPFDVGIKLSGAQYQQHGRAL
Physicochemical Analysis
2517.79 Da
8.60
0.85
0.59
0.0368
-0.29
0.41
0.08
13.81
76.52
0.1304
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1061.45
-10.75
35.0
34.0
81.0
179.0
5.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0216716 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
motilin family
10090; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone motilin family
PaperPDB 2JSJ structural record; NMR; chain A; residues 1-23
RECORD: Rec_0242087 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Proghrelin-derived peptide
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Hormonal Appetite regulation
Mouse plasma
HPLC, LC-UV/MS
42.2 [40.5, 44.0] min
PaperIn vitro metabolic stability of obestatin: kinetics and identification of cleavage products
RECORD: Rec_0243499 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Proghrelin-derived peptide
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Hormonal Appetite regulation
Membrane brain homogenate of mouse
HPLC
27 min
PaperCentral administration of obestatin fails to show inhibitory effects on food and water intake in mice
RECORD: Rec_0426731 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Proghrelin-derived peptide
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Hormonal Appetite regulation
Crude brain homogenate of mouse
HPLC
19 min
PaperCentral administration of obestatin fails to show inhibitory effects on food and water intake in mice
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