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MYP_033923
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Basic Information
Obestatin-23
Cardiovascular
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Sleep regulation
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
23 amino acids
C114H173N33O32
Standard
Sequence
FNAPFDVGIKLSGAQYQQHGRAL
Physicochemical Analysis
2517.79 Da
8.60
0.85
0.59
0.0368
-0.29
0.41
0.08
13.81
76.52
0.1304
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1061.45
-10.75
35.0
34.0
81.0
179.0
5.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014686 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Motilin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Gastrointestinal
Evidence URLhttps://www.uniprot.org/uniprotkb/GHRL_RAT/entry
RECORD: Rec_0041129 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Motilin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Gastrointestinal
Evidence URLhttps://www.uniprot.org/uniprotkb/GHRL_MOUSE/entry
RECORD: Rec_0060709 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Obestatin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation Sleep regulation Wake regulation Feeding regulator
Experimental: 22±2 minutes; /1320 seconds; Mammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Obestatin-23 (Rattus norvegicus): PMID 16284174##17204551 PMID16284174;17204551 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16284174/
RECORD: Rec_0076029 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Proghrelin-derived peptide
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Hormonal Appetite regulation
Mouse stomach homogenate
HPLC, LC-UV/MS
30.0 [27.8, 32.6] min
PaperIn vitro metabolic stability of obestatin: kinetics and identification of cleavage products
RECORD: Rec_0131792 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Obestatin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation Sleep regulation Wake regulation Feeding regulator
Experimental: 22±2 minutes; /1320 seconds; Mammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Obestatin (Mus musculus): PMID 17204551 PMID17204551 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17204551/
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