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MYP_033904
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Basic Information
N-(Picolinoyl)-Lys-boroMet
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
2 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0108676 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Boronated methionine at C terminus at 2; Boronated methionine at C terminus; Boronated methionine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Mycobacterium tuberculosis
0.34 μM
MIC
PMID25759383 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25759383/
RECORD: Rec_0145382 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0175223 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
L=lauric acid
Bio-Activity Profile
Antiparasitic Antimicrobial Antiplasmodial
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
RECORD: Rec_0185311 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Boronated methionine at C terminus at 2; Boronated methionine at C terminus; Boronated methionine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Mycobacterium tuberculosis
0.065 μM
MIC
PMID25759383 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25759383/
RECORD: Rec_0236302 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Oligo-acyl-lysyl
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
L=lauric acid
Bio-Activity Profile
Antimicrobial Antimalarial Antiparasitic
Plasmodium falciparum W2
68.2 μM
IC50; [3H] Hypoxanthine incorporation assay
PMID17307975 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17307975/
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