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MYP_033898
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Basic Information
Brevinin-1CG2
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
24 amino acids
C123H207N29O27S2
Standard
Sequence
FLPIVAGLAANFLPKIVCKITKKC
Physicochemical Analysis
2588.27 Da
9.70
3.74
3.50
0.1557
1.08
0.68
0.34
5.22
134.17
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
882.44
-3.04
31.0
33.0
84.0
181.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017058 VERIFIED: YES
Provenance & Taxonomy
Amolops chunganensis [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID22951323 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22951323/
RECORD: Rec_0064210 VERIFIED: YES
Provenance & Taxonomy
Amolops chunganensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
Enterococcus faecalis 981
19 μM
MIC
PaperCharacterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis
RECORD: Rec_0067854 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 50.0%, E 0.0%, T 29.2%, C 20.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Antifungal Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0078884 VERIFIED: YES
Provenance & Taxonomy
Amolops chunganensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Staphylococcus aureus
9 μM
MIC
RECORD: Rec_0088149 VERIFIED: YES
Provenance & Taxonomy
Amolops chunganensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
Pseudomonas aeruginosa CGMCC 1.50
>150 μM
MIC
PaperCharacterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis
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