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MYP_033896
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Basic Information
O-2 (Oncocin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Standard
18 amino acids
C103H164N32O24
Standard
Sequence
VDKPPYLPRPRPPRRIYN
Physicochemical Analysis
2234.60 Da
10.93
3.73
3.52
0.2073
-1.59
0.49
-0.47
64.94
59.44
0.1111
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
899.75
-6.15
30.0
28.0
62.0
159.0
8.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0096685 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Oncocin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Micrococcus luteus ATCC 10240
128 μg/mL
MIC
Mouse serum: The half-life is 120 min in 25% aqueous mouse serum
PaperKnappe D, Kabankov N, Hoffmann R Bactericidal oncocin derivatives with superior serum stabilities Int J Antimicrob Agents. 2011 Feb;37(2):166-70. PMID:21185160 https://pubmed.ncbi.nlm.nih.gov/21185160/ PMID21185160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21185160/
RECORD: Rec_0240945 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli DSM 10233
125 μg/mL
MIC
PMID19400239 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19400239/
RECORD: Rec_0257193 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Oncocin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli BL21AI
64 μg/mL
MIC
Mouse serum: The half-life is 120 min in 25% aqueous mouse serum
PaperKnappe D, Kabankov N, Hoffmann R Bactericidal oncocin derivatives with superior serum stabilities Int J Antimicrob Agents. 2011 Feb;37(2):166-70. PMID:21185160 https://pubmed.ncbi.nlm.nih.gov/21185160/ PMID21185160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21185160/
RECORD: Rec_0319316 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis DSM 347
125 μg/mL
MIC
PMID19400239 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19400239/
RECORD: Rec_0349294 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Micrococcus luteus DSM 1790
15.6 μg/mL
MIC
PMID19400239 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19400239/
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