Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC393H623N111O104S9

DescriptionStandard

        MVLIRKMFYFVFAVFFILAQRPSGSQAGLDFSQPFSSGEFAVCESCKLGRGKCRKECLESEKAVGSCRLNFLCCRRRI
    

Molecular Weight8855.42 Da

Isoelectric Point (pI)9.36

Net Charge (pH 7.0)6.44

Net Charge (pH 7.4) 6.10

Charge Density (pH 7.0) 0.0826

GRAVY Index0.16

Hydrophobic Moment 0.48

Boman Index0.00

Instability Index68.33

Aliphatic Index 75.00

Aromaticity 0.1282

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3489.97

LogP -32.32

H-bond Donors 132.0

H-bond Acceptors 120.0

Rotatable Bonds 299.0

Heavy Atoms 617.0

Ring Count 12.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0154972 VERIFIED: NO

Provenance & Taxonomy

OrganismAotus nancymaae [Animal]

FamilyDefensin

Tax ID37293

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence