Peptide Database

Peptide NameTumor necrosis factor ligand superfamily member 4

Function Ontology

Anticancer ▸ tumor necrosis factor family

Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide

Immunology ▸ Immune modulation ▸ Cytokine modulation

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length148 amino acids

Chemical FormulaC743H1165N197O224S6

DescriptionStandard

        SSSPAKDPPIQRLRGAVTRCEDGQLFISSYKNEYQTMEVQNNSVVIKCDGLYIIYLKGSFFQEVKIDLHFREDHNPISIPMLNDGRRIVFTVVASLAFKDKVYLTVNAPDTLCEHLQINDGELIVVQLTPGYCAPEGSYHSTVNQVPL
    

Molecular Weight16633.77 Da

Isoelectric Point (pI)5.49

Net Charge (pH 7.0)-4.21

Net Charge (pH 7.4) -4.72

Charge Density (pH 7.0) -0.0285

GRAVY Index-0.16

Hydrophobic Moment 0.58

Boman Index0.05

Instability Index25.73

Aliphatic Index 94.73

Aromaticity 0.0878

Extinction Coeff. Reduced 10430.00

Extinction Coeff. Oxidized 10680.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6759.46

LogP -64.75

H-bond Donors 231.0

H-bond Acceptors 230.0

Rotatable Bonds 544.0

Heavy Atoms 1170.0

Ring Count 26.0

Amide Bonds 163.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0325587 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

Familytumor necrosis factor family

Tax ID10090; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide20-113; 48-133

Bio-Activity Profile

Function

Cytokine Growth factor tumor necrosis factor family Chemokine-like Host defense