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MYP_033810
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Basic Information
Ir-Def2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
37 amino acids
C185H282N58O46S6
Standard
Sequence
GGYYCPFRQDKCHRHCRSFGRKAGYCGGFLKKTCICV
Physicochemical Analysis
4246.97 Da
9.46
6.87
6.47
0.1857
-0.51
0.80
-0.15
55.23
31.62
0.1622
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1692.71
-17.32
68.0
61.0
138.0
295.0
9.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0433469 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
disulfide-constrained linear peptide [Linear]
canonical L-amino-acid peptide [L]
5-26; 12-34; 16-36
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus luteus
25 μM
MMC
PaperFunctional characterization of two defensin isoforms of the hard tick Ixodes ricinus. PMID21504572
RECORD: Rec_0433470 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
disulfide-constrained linear peptide [Linear]
canonical L-amino-acid peptide [L]
5-26; 12-34; 16-36
Bio-Activity Profile
Antimicrobial
Escherichia coli
>50 μM
MIC (no effect up to 50 μM)
PaperFunctional characterization of two defensin isoforms of the hard tick Ixodes ricinus. PMID21504572
RECORD: Rec_0433471 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
disulfide-constrained linear peptide [Linear]
canonical L-amino-acid peptide [L]
5-26; 12-34; 16-36
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa
>100 μM
MIC (no effect up to 100 μM)
PaperFunctional characterization of two defensin isoforms of the hard tick Ixodes ricinus. PMID21504572
RECORD: Rec_0433472 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
disulfide-constrained linear peptide [Linear]
canonical L-amino-acid peptide [L]
5-26; 12-34; 16-36
Bio-Activity Profile
Antimicrobial
Candida albicans
>100 μM
MIC (no effect up to 100 μM)
PaperFunctional characterization of two defensin isoforms of the hard tick Ixodes ricinus. PMID21504572
RECORD: Rec_0433473 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
disulfide-constrained linear peptide [Linear]
canonical L-amino-acid peptide [L]
5-26; 12-34; 16-36
Bio-Activity Profile
Antimicrobial
Tick-borne encephalitis virus (TBEV)
>100 μM
virus inhibition assay (no effect at 100 μM)
PaperFunctional characterization of two defensin isoforms of the hard tick Ixodes ricinus. PMID21504572
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