‹ ›
MYP_033810
← PREVIOUS NEXT → BACK
Basic Information
Ir-Def2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
37 amino acids
C185H282N58O46S6
Standard
Sequence
GGYYCPFRQDKCHRHCRSFGRKAGYCGGFLKKTCICV
Physicochemical Analysis
4246.97 Da
9.46
6.87
6.47
0.1857
-0.51
0.80
-0.15
55.23
31.62
0.1622
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1692.71
-17.32
68.0
61.0
138.0
295.0
9.0
37.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0060454 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-26, 12-34, 16-36
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus (MRSA)
25 μM
MIC
PMID21504572 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21504572/
RECORD: Rec_0098207 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-26, 12-34, 16-36
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Hemolytic
PMID21504572 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21504572/
RECORD: Rec_0184307 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-26, 12-34, 16-36
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Micrococcus luteus
0.37 μM
MIC
PMID21504572 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21504572/
RECORD: Rec_0290038 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-26, 12-34, 16-36
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Hemolytic
human erythrocytes
PMID21504572 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21504572/
RECORD: Rec_0308168 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Ir
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperParasit Vectors. 2011 Apr 19;4:63. | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102633/ Evidence URLhttps://pmc.ncbi.nlm.nih.gov/articles/PMC3102633/
FIRST PREV 1 2 3 NEXT LAST
Showing 5 records on this page · Page 2 of 3