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MYP_033790
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Basic Information
Defensin heliomicin (Insects, animals)
Antimicrobial
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
44 amino acids
C201H303N61O64S6
Standard
Sequence
DKLIGSCVWGAVNYTSDCNGECKRRGYKGGHCGSFANVNCWCET
Physicochemical Analysis
4790.32 Da
7.77
0.79
0.44
0.0180
-0.47
0.55
-0.04
32.42
42.05
0.1136
13980.00
14355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2039.91
-26.27
78.0
72.0
155.0
332.0
8.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0305505 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Evidence URLhttps://patents.google.com/patent/US20030208035A1/en PatentUS 2003/0208035 A1
RECORD: Rec_0316129 VERIFIED: YES
Provenance & Taxonomy
Heliothis virescens [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
F. culmorum
0.2-0.4 μM
MIC
PMID10092609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10092609/
RECORD: Rec_0326545 VERIFIED: YES
Provenance & Taxonomy
Heliothis virescens [Animal]
invertebrate defensin family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-32; 18-40; 22-42
Bio-Activity Profile
Antimicrobial invertebrate defensin family Antifungal Host defense Defensin-like
PaperPDB 1I2V structural record; NMR; chain A; residues 1-44
RECORD: Rec_0334716 VERIFIED: YES
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID20096726 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20096726/
RECORD: Rec_0367973 VERIFIED: YES
Provenance & Taxonomy
Heliothis virescens [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
None
None
7-32, 18-40, 22-42
Bio-Activity Profile
Antimicrobial Antifungal
Trichoderma viride
1.5-3 μM
MIC
PMID10092609;11580275 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10092609/
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