‹ ›
MYP_033790
← PREVIOUS NEXT → BACK
Basic Information
Defensin heliomicin (Insects, animals)
Antimicrobial
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
44 amino acids
C201H303N61O64S6
Standard
Sequence
DKLIGSCVWGAVNYTSDCNGECKRRGYKGGHCGSFANVNCWCET
Physicochemical Analysis
4790.32 Da
7.77
0.79
0.44
0.0180
-0.47
0.55
-0.04
32.42
42.05
0.1136
13980.00
14355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2039.91
-26.27
78.0
72.0
155.0
332.0
8.0
47.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0083120 VERIFIED: YES
Provenance & Taxonomy
Heliothis virescens [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
T. viride
1.5-3 μM
MIC
PMID10092609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10092609/
RECORD: Rec_0090950 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Heliothis virescens [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
3 Disulphide bridges:7,32; 18,40; 22,42
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
PaperSolution Structures of the Antifungal Heliomicin and a Selected Variant with Both Antibacterial and Antifungal Activities.
RECORD: Rec_0096977 VERIFIED: YES
Provenance & Taxonomy
Heliothis virescens [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
N. haematococca
0.4-0.8 μM
MIC
PMID10092609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10092609/
RECORD: Rec_0138621 VERIFIED: NO
Provenance & Taxonomy
Heliothis virescens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
RECORD: Rec_0178627 VERIFIED: YES
Provenance & Taxonomy
Heliothis virescens [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
None
None
7-32, 18-40, 22-42
Bio-Activity Profile
Antimicrobial Antifungal
Neurospora crassa
0.1-0.2 μM
MIC
PMID10092609;11580275 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10092609/
FIRST PREV 1 2 3 4 5 NEXT LAST
Showing 5 records on this page · Page 2 of 5