MYP_033786
Basic Information
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
not Standard
19 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XPAXXFXPAXXLXXLXXLX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014421 VERIFIED: YES
Provenance & Taxonomy
Peptaibols [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Aminoethanol
X(1/4/5/17)=Aib=1-amino-isobutyric acid; X(7/13/16)=Iva=Isovaline; X(10)=AHMA=3-amino-2-hydroxy-3-methylbutanoic acid; X(11/14/19)(β)A=β-Alanine
Bio-Activity Profile
Antimicrobial Anticancer
BGC-823
2.11 μM
IC50
RECORD: Rec_0093674 VERIFIED: YES
Provenance & Taxonomy
Peptaibols [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Aminoethanol
X(1/4/5/16/17)=Aib=1-amino-isobutyric acid; X(7/13)=Iva=Isovaline; X(10)=AHMA=3-amino-2-hydroxy-3-methylbutanoic acid; X(11/14/19)(β)A=β-Alanine
Bio-Activity Profile
Antimicrobial Anticancer
HCT 8
5.93 μM
IC50
RECORD: Rec_0099734 VERIFIED: YES
Provenance & Taxonomy
Peptaibols [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Aminoethanol
X(1/4/5/16/17)=Aib=1-amino-isobutyric acid; X(7/13)=Iva=Isovaline; X(10)=AHMA=3-amino-2-hydroxy-3-methylbutanoic acid; X(11/14/19)(β)A=β-Alanine
Bio-Activity Profile
Antimicrobial Anticancer
A2780
3.79 μM
IC50
RECORD: Rec_0112716 VERIFIED: YES
Provenance & Taxonomy
Peptaibols [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Aminoethanol
X(1/4/5/16/17)=Aib=1-amino-isobutyric acid; X(7/13)=Iva=Isovaline; X(10)=AHMA=3-amino-2-hydroxy-3-methylbutanoic acid; X(11/14/19)(β)A=β-Alanine
Bio-Activity Profile
Antimicrobial Anticancer
BEL-7402
1.98 μM
IC50
RECORD: Rec_0113627 VERIFIED: YES
Provenance & Taxonomy
Peptaibols [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Aminoethanol
X(1/4/5/17)=Aib=1-amino-isobutyric acid; X(7/13/16)=Iva=Isovaline; X(10)=AHMA=3-amino-2-hydroxy-3-methylbutanoic acid; X(11/14/19)(β)A=β-Alanine
Bio-Activity Profile
Antimicrobial Anticancer
BEL-7402
1.94 μM
IC50
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