MYP_033778
Insectotoxin I5A
Annotation / Sequence feature
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Nuclear export signal
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Immunology
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Innate immune defense
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Host defense peptide
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Host defense activity
Membrane / Ion-channel modulation
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Chloride channel modulation
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Chloride channel inhibitor
Membrane / Ion-channel modulation
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Ion channel inhibition
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
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General toxin
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Toxic
Venom / Toxin
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General toxin
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Toxin
Venom / Toxin
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Toxin
Standard
35 amino acids
C152H246N48O46S11
Standard
MCMPCFTTDPNMAKKCRDCCGGNGKCFGPQCLCNR
3834.59 Da
8.50
2.42
2.08
0.0692
-0.36
0.45
-0.12
36.19
14.00
0.0571
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1515.63
-20.31
58.0
60.0
124.0
257.0
5.0
38.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0122322
VERIFIED: NO
Provenance & Taxonomy
Buthus eupeus [Animal]; Mesobuthus eupeus [Animal]; Caucasus subspecies [Animal]
Structure & Mods
linear disulfide-stabilized peptide [Linear]
canonical L-amino-acid peptide [L]
2-19, 5-26, 16-31, 20-33
Bio-Activity Profile
Toxin
RECORD: Rec_0179703
VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 22.9%, E 28.6%, T 25.7%, C 22.9% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic
Cytotoxic
RECORD: Rec_0305664
VERIFIED: YES
Provenance & Taxonomy
Mesobuthus eupeus [Animal]
Chloride channel inhibitor family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
2-19; 5-26; 16-31; 20-33
Bio-Activity Profile
Toxin
Venom
Chloride channel inhibitor family
Pathogenesis-associated
Host defense