Peptide Database

Peptide NameProgonadoliberin-1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC351H537N101O108S4

DescriptionStandard

        QHWSYGLSPGGKRDLDSLSDTLGDIIERFPHADSPCSVLGCAEEPPFPKMYRMKGFIGSGTDRDNGHRTYKK
    

Molecular Weight8027.89 Da

Isoelectric Point (pI)7.01

Net Charge (pH 7.0)0.01

Net Charge (pH 7.4) -0.40

Charge Density (pH 7.0) 0.0001

GRAVY Index-0.86

Hydrophobic Moment 0.69

Boman Index-0.13

Instability Index50.57

Aliphatic Index 50.14

Aromaticity 0.0972

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3340.28

LogP -36.73

H-bond Donors 118.0

H-bond Acceptors 115.0

Rotatable Bonds 260.0

Heavy Atoms 564.0

Ring Count 17.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0350097 VERIFIED: NO

Provenance & Taxonomy

OrganismPagrus major [Animal]

FamilyProgonadoliberin

Tax ID143350

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour