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MYP_033700
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Basic Information
Alpha-1-purothionin (Plant defensin)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
45 amino acids
C198H340N68O56S8
Standard
Sequence
KSCCRSTLGRNCYNLCRARGAQKLCAGVCRCKISSGLSCPKGFPK
Physicochemical Analysis
4825.76 Da
9.75
9.67
9.35
0.2150
-0.26
0.69
-0.19
39.54
56.44
0.0444
1490.00
1990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2036.62
-28.21
82.0
74.0
163.0
330.0
4.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0161582 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
S. uvarum CC-21
32 μg/mL
MIC
PaperInhibition of brewer's yeasts by wheat purothionins.
RECORD: Rec_0175409 VERIFIED: NO
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0241753 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
Thionin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas solanacearum
3 μg/mL
MIC
PMID5031563 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5031563/
RECORD: Rec_0332164 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
plant thionin (TC 1.C.44) family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-39; 4-31; 12-29; 16-25
Bio-Activity Profile
Toxin Venom plant thionin (TC 1.C.44) family Host defense
PaperPDB 2PLH structural record; X-ray; 2.50 A; chain A; residues 1-45
RECORD: Rec_0345338 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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