Peptide Database

Peptide NameCGEN-857

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC94H144N32O21S2

DescriptionStandard

        SMCHRWSRAVLFPAAHRP
    

Molecular Weight2122.48 Da

Isoelectric Point (pI)11.70

Net Charge (pH 7.0)2.62

Net Charge (pH 7.4) 2.30

Charge Density (pH 7.0) 0.1458

GRAVY Index-0.28

Hydrophobic Moment 0.58

Boman Index-0.09

Instability Index97.46

Aliphatic Index 54.44

Aromaticity 0.1111

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 839.75

LogP -7.23

H-bond Donors 32.0

H-bond Acceptors 28.0

Rotatable Bonds 62.0

Heavy Atoms 149.0

Ring Count 7.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076121 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetMAS1 (Human)

Activity1000 nM

MethodEC50