Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC458H763N139O119S8

DescriptionStandard

        MKLLFLFLAILLAREPVVSAQCWKDGHCRLVCKDSEDSVIRCANRKRCCVPSRYLTIQPVTIHGVLNWTTPQMPTTAQKKKKKKRKRTHG
    

Molecular Weight10377.34 Da

Isoelectric Point (pI)10.18

Net Charge (pH 7.0)13.70

Net Charge (pH 7.4) 13.22

Charge Density (pH 7.0) 0.1522

GRAVY Index-0.36

Hydrophobic Moment 0.63

Boman Index-0.15

Instability Index47.93

Aliphatic Index 84.44

Aromaticity 0.0556

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4196.11

LogP -38.75

H-bond Donors 155.0

H-bond Acceptors 144.0

Rotatable Bonds 350.0

Heavy Atoms 724.0

Ring Count 15.0

Amide Bonds 95.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0213966 VERIFIED: NO

Provenance & Taxonomy

OrganismDipodomys ordii [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic