Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length440 amino acids

Chemical FormulaC2210H3477N603O611S9

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGIVILQKELAQLKLPDISGDFRIRHVGKVRYEISRLSLRSFHLPYSRISLVPNVGLQVSISNAFAEVDGNWRVKIHFIRDHGSFDLKVENIYIKINLRLGSDTSGKPTIDTSDCSTRISKVRVRFSGKFGWLYNLFHSAVESRFRKILESKVCERRGQSSGSFWWSSALPFTAKIDAMSGIDYSLVAPPTATAQSLDVKLKGEFFSLANRSAVPFPPLALAFPPDHDRMVYFGASSYFFNTAGFVYHTAGALVFEVTDSMIPKGIDFHLNTSTFSAFIPQLEKMYPDRLMKLRLSAPSAPFLNIGPGGLSLKPVVDIQAYAILPNSSLAPLFLLSLTCNVSAVIDVRSGRIVGSLKVGRYEGEAARGGAGAAPVRTLQSIMNIVASSILLPRLNARLDQGFPLPLPDRIQLSNILVRFHQ
    

Molecular Weight48558.51 Da

Isoelectric Point (pI)9.81

Net Charge (pH 7.0)16.27

Net Charge (pH 7.4) 15.45

Charge Density (pH 7.0) 0.0370

GRAVY Index0.07

Hydrophobic Moment 0.66

Boman Index0.10

Instability Index35.64

Aliphatic Index 98.84

Aromaticity 0.1000

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 40005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0208737 VERIFIED: NO

Provenance & Taxonomy

OrganismPodilymbus podiceps [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria