Peptide Database

Peptide NameDefensin alpha 6

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC459H725N133O156S8

DescriptionStandard

        MRTLTFLAAILLVALQAQAEPLQAEDEPLQASAYEADAQEQRGADNQDFTISFAGDANSSLRALGSTRSFTCNCRRSCYSTENSYGTCTVMGVTNRFCCL
    

Molecular Weight10858.98 Da

Isoelectric Point (pI)4.54

Net Charge (pH 7.0)-4.54

Net Charge (pH 7.4) -4.86

Charge Density (pH 7.0) -0.0454

GRAVY Index-0.17

Hydrophobic Moment 0.57

Boman Index-0.01

Instability Index52.39

Aliphatic Index 69.50

Aromaticity 0.0800

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4712.15

LogP -61.50

H-bond Donors 170.0

H-bond Acceptors 160.0

Rotatable Bonds 357.0

Heavy Atoms 756.0

Ring Count 10.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0379153 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic