Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC170H276N48O57S2

DescriptionStandard

        KCNTATCVTQRLADFLVRSSNTIGTVYVPTNVGSSTY
    

Molecular Weight3968.43 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0470

GRAVY Index0.03

Hydrophobic Moment 0.68

Boman Index0.05

Instability Index11.24

Aliphatic Index 76.22

Aromaticity 0.0811

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1724.60

LogP -24.27

H-bond Donors 64.0

H-bond Acceptors 61.0

Rotatable Bonds 125.0

Heavy Atoms 277.0

Ring Count 4.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0398381 VERIFIED: YES

Provenance & Taxonomy

OrganismXiphophorus maculatus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)