Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC360H579N103O111S10

DescriptionStandard

        MEKKSIAGLCFLLLLLFVAQEVVVQSEAKTCENLADTYKGPCFTTGSCDDHCKNKEHLISGRCRDDVRCWCTRNC
    

Molecular Weight8446.72 Da

Isoelectric Point (pI)6.68

Net Charge (pH 7.0)-0.40

Net Charge (pH 7.4) -0.87

Charge Density (pH 7.0) -0.0054

GRAVY Index-0.16

Hydrophobic Moment 0.50

Boman Index-0.05

Instability Index32.29

Aliphatic Index 76.67

Aromaticity 0.0667

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3475.55

LogP -36.87

H-bond Donors 130.0

H-bond Acceptors 123.0

Rotatable Bonds 285.0

Heavy Atoms 584.0

Ring Count 9.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0297745 VERIFIED: NO

Provenance & Taxonomy

OrganismMucuna pruriens [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal