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MYP_033445
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Basic Information
Hadrurin/Vejovine based peptide, H/V-peptide
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
29 amino acids
C137H252N42O37
Standard
Sequence
GILKTIKSIASKVANTVQKLKRKAKNAVA
Physicochemical Analysis
3079.73 Da
11.47
7.75
7.54
0.2673
-0.10
0.70
-0.10
7.04
114.48
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1332.35
-14.17
47.0
45.0
113.0
216.0
0.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007749 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Escherichia coli 170
3.1 μM
MIC
PMID23403131 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23403131/
RECORD: Rec_0018466 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
46 μM
EC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/23403131/ PMID23403131 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23403131/
RECORD: Rec_0019263 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Salmonella typhimurium
1.6-6.2 μM
MIC
PMID23403131 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23403131/
RECORD: Rec_0078987 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0094331 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Plasmodium berghei[40-50% Inhibition = 5 microM
PMID23403131 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23403131/
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