Peptide Database

Peptide NameTrypsin inhibitor CMTI-III

Function Ontology

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC135H226N40O40S7

DescriptionStandard

        RVCPRILMKCKKDSDCLAECVCLEHGYCG
    

Molecular Weight3273.94 Da

Isoelectric Point (pI)7.78

Net Charge (pH 7.0)0.79

Net Charge (pH 7.4) 0.44

Charge Density (pH 7.0) 0.0273

GRAVY Index0.02

Hydrophobic Moment 0.61

Boman Index-0.08

Instability Index43.71

Aliphatic Index 77.24

Aromaticity 0.0345

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1289.53

LogP -11.91

H-bond Donors 51.0

H-bond Acceptors 49.0

Rotatable Bonds 110.0

Heavy Atoms 222.0

Ring Count 3.0

Amide Bonds 28.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0065891 VERIFIED: NO

Provenance & Taxonomy

OrganismCucurbita maxima [Plant]; Luffa cylindrica [Plant]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-20; 10-22; 16-28

Bio-Activity Profile

Function

Enzyme inhibitory

RECORD: Rec_0344413 VERIFIED: YES