Peptide Database

Peptide NameSLAY-screened peptide P5699

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC102H148N22O32S

DescriptionStandard

        ATSVPCSFPLYTASNYYITQ
    

Molecular Weight2226.46 Da

Isoelectric Point (pI)5.56

Net Charge (pH 7.0)-0.22

Net Charge (pH 7.4) -0.42

Charge Density (pH 7.0) -0.0109

GRAVY Index0.14

Hydrophobic Moment 0.21

Boman Index0.25

Instability Index23.14

Aliphatic Index 63.50

Aromaticity 0.2000

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 866.89

LogP -9.31

H-bond Donors 31.0

H-bond Acceptors 33.0

Rotatable Bonds 62.0

Heavy Atoms 157.0

Ring Count 6.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0337199 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/